Evolyssein Sarasota

Next-generation HA filler with Cold-X™ Technology for smoother, natural-looking smile and laugh lines that last up to a year.

blond woman getting a botoxoxation from a beauper

Holcomb–Kreithen Medspa: Where Innovation Meets Expertise

At Holcomb–Kreithen Medspa, we pride ourselves on offering only the most advanced, effective aesthetic treatments. Our expert providers deliver personalized care rooted in precision, safety, and artistry, hallmarks of our practice. Evolysse Filler is the latest breakthrough in injectable hyaluronic acid technology, designed to smooth smile and laugh lines with unparalleled naturalness. Developed by global aesthetic leaders and supported by rigorous clinical research, Evolysse represents a new era in facial rejuvenation.

Book your consultation with us today and discover how Evolysse can help you look as confident as you feel.

What is Evolysse Filler?

Evolysse is a new collection of injectable hyaluronic acid (HA) fillers made with exclusive Cold-X™ Technology, the first innovation of its kind in over a decade. This advanced process preserves the natural structure of HA using near-freezing temperatures, allowing the filler to integrate beautifully into facial tissue for a look and feel that’s remarkably natural.

The first two FDA-approved formulations, Evolysse Form and Evolysse Smooth, are designed to soften nasolabial folds, commonly known as smile and laugh lines, with results that can last up to 12 months in most patients.

Benefits of Evolysse Filler

Natural-looking results with Cold-X™ Technology
Clinically proven to smooth smile and laugh lines
Comfortable, tissue-friendly integration
Long-lasting improvement—up to 12 months
FDA-approved with a strong safety profile
Ideal for dynamic expressions—smile and relax with confidence

Am I a Good Candidate for Evolysse Filler?

If you’re looking to reduce the appearance of nasolabial folds without surgery, you may be a candidate for Evolysse. This treatment is ideal for healthy adults experiencing volume loss due to aging or weight changes who want natural, subtle results.

Our team will perform a thorough consultation to ensure this treatment is right for your goals and anatomy.

What to Expect During Evolysse Filler Treatment

Your appointment will begin with a personalized evaluation and discussion of your aesthetic goals. Once a treatment plan is in place, our injector will use a fine needle to administer the filler precisely into targeted areas around your mouth and cheeks.

The process typically takes less than 30 minutes and involves minimal discomfort, with most patients returning to normal activities the same day.

Evolysse Filler Recovery and Results

After treatment, you may experience mild swelling, redness, or tenderness at the injection sites. These effects are temporary and generally resolve within a few days. Results are visible almost immediately and continue to improve as any swelling subsides.

In clinical studies, most patients reported smoother-looking smile and laugh lines when both smiling and at rest, with results lasting up to 12 months.

Why Choose Holcomb–Kreithen Medspa for Evolysse Filler?

Our highly trained injectors are part of a renowned aesthetic team led by double board-certified surgeons Dr. J. David Holcomb and Dr. Joshua Kreithen. With decades of combined experience in facial rejuvenation, Holcomb–Kreithen Medspa brings unmatched precision and an artist’s eye to every injectable treatment.

We stay at the forefront of technological advancements, offering cutting-edge solutions like Evolysse to our Sarasota and Tampa patients in a safe, supportive environment.

Holcomb - Kreithen Plastic Surgery & Medspa

Evolysse FAQs

Is Evolysse Filler safe for all skin types and tones?

Yes, Evolysse has been shown to be safe across a range of skin types and tones. Our team is experienced in customizing injectable treatments for diverse aesthetic needs.

Are there any specific medications or supplements I should avoid before receiving Evolysse?

Yes, patients are advised to avoid blood-thinning medications and supplements such as aspirin, ibuprofen, fish oil, and vitamin E for at least a week before treatment to reduce the risk of bruising. Always consult your provider for a full list.

What are the risks and side effects associated with Evolysse Filler?

Common side effects include temporary redness, swelling, bruising, and tenderness at the injection site. Rare risks include allergic reactions, infection, or vascular complications. All potential risks will be discussed thoroughly during your consultation.

How soon after treatment can I resume physical activity or exercise?

Most patients can return to light activity the same day, but it’s recommended to avoid strenuous exercise, heat exposure, and alcohol for at least 24–48 hours post-treatment.

How often can I receive Evolysse Filler treatments?

Most patients repeat treatment annually, but retreatment timing depends on individual metabolism, aesthetic goals, and how the filler settles over time.